Posted by: jeanne | May 16, 2011

curing cancer the easy and cheap way?

Canadian researchers find a simple cure for cancer, but major pharmaceutical companies are not interested.

Researchers at the University of Alberta, in Edmonton, Canada have cured cancer last week, yet there is a little ripple in the news or in TV. It is a simple technique using very basic drug. The method employs dichloroacetate, which is currently used to treat metabolic disorders. So, there is no concern of side effects or about their long term effects.

This drug doesn’t require a patent, so anyone can employ it widely and cheaply compared to the costly cancer drugs produced by major pharmaceutical companies.

Canadian scientists tested this dichloroacetate (DCA) on human’s cells; it killed lung, breast and brain cancer cells and left the healthy cells alone. It was tested on Rats inflicted with severe tumors; their cells shrank when they were fed with water supplemented with DCA. The drug is widely available and the technique is easy to use, why the major drug companies are not involved? Or the Media interested in this find?

In human bodies there is a natural cancer fighting human cell, the mitochondria, but they need to be triggered to be effective. Scientists used to think that these mitochondria cells were damaged and thus ineffective against cancer. So they used to focus on glycolysis, which is less effective in curing cancer and more wasteful. The drug manufacturers focused on this glycolysis method to fight cancer. This DCA on the other hand doesn’t rely on glycolysis instead on mitochondria; it triggers the mitochondria which in turn fights the cancer cells.

The side effect of this is it also reactivates a process called apoptosis. You see, mitochondria contain an all-too-important self-destruct button that can’t be pressed in cancer cells. Without it, tumors grow larger as cells refuse to be extinguished. Fully functioning mitochondria, thanks to DCA, can once again die.

With glycolysis turned off, the body produces less lactic acid, so the bad tissue around cancer cells doesn’t break down and seed new tumors.

Pharmaceutical companies are not investing in this research because DCA method cannot be patented, without a patent they can’t make money, like they are doing now with their AIDS Patent. Since the pharmaceutical companies won’t develop this, the article says other independent laboratories should start producing this drug and do more research to confirm all the above findings and produce drugs. All the groundwork can be done in collaboration with the Universities, who will be glad to assist in such research and can develop an effective drug for curing cancer.

You can access the original research for this cancer here.

This article wants to raise awareness for this study, hope some independent companies and small startup will pick up this idea and produce these drugs, because the big companies won’t touch it for a long time.

but also this:

Andy Coghlan, reporter

So, we hear news of a miraculous treatment for cancer. Disappointingly, the story is an old one which has somehow resurfacedon the blogosphere.
When we originally published the story four years ago, it created a frenzy on the internet which took us by surprise. Our story reported a new type of treatment that in animal experiments showed promise of potentially being able to tackle most types of human cancer.
We often report developments in cancer research, but nothing had ever attracted such a wave of interest. The drug involved, a simple molecule called dichloro-acetate, or DCA, appeared to work by blocking the unusual, sugar-gobbling mechanism called glycolysis by which most cancer cells generate their energy, and so which potentially marks them out from healthy cells.
Exposed to DCA, cancer cells stopped making energy from sugar and resumed making it the way healthy cells do, in chambers called mitochondria. This stopped cancer cells from growing and multiplying, and caused them to wither and die instead.
What added to the intrigue was that DCA is such a cheap, simple molecule that no-one has ever patented it. Also, it was already being used to treat rare mitochondrial diseases. Within weeks, patients were trying to get their own supplies of DCA, and some entrepreneurs set up websites to sell it, that were subsequently declared illegal and closed down by the US Food and Drug Administration.
So what happened after the frenzy died down?
The answer is that it was finally tested in five patients with aggressive brain cancer by Evangelos Michelakis of the University of Alberta in Edmonton, Canada, who had conducted the original experiments in animals.
The results, published last year in Science Translational Medicine, revealed that it probably extended the lives of four of the patients, while one other died.
Most importantly, Michelakis demonstrated from brain scans and biopsies that DCA appeared to work as he had predicted, arresting the growth of cancer cells by switching them back to normal energy production in mitochondria. The experiments also showed that beneficial effects took a few months to kick in. Importantly, Michelakis said that despite the small trial, it would be impossible to tell whether DCA works or not until it is tested in a placebo-controlled trial.
As far as we know, no further trials have been conducted, so the jury is still out on whether it may do any good. We reported the new results in New Scientist and included news of other teams around the world developing treatments targeting glycolysis.
Some other treatments that disrupt energy metabolism, such as the drug metformin taken by diabetics, were also showing signs of activity against cancer, for example. So for now, we are a little bit wiser about how DCA might work, but until someone does a much larger, well-organised trial, it would be unwise to assume that taking it will be safe or do any good.
The more encouraging news is that other teams are now investigating the scope for targeting glycolysis, and although it could be a long haul to demonstrate whether any work, it does provide another avenue of attack against a disease which continues to push medicine to its limits.
Any readers wanting to find out more about DCA may find this blog useful, posted by Cancer Research UK.
There’s also an excellent blog by National Geographic which goes into even more detail.
so?

Responses

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  4. Thanks for the exposition of A basic cause of the initiation of SOME cancer. Cancer has been such a mystery for the layman and cancer professional alike because it has been SHROUDED in mystery and medical-techno-babble. I am thrilled to see articles such as yours that brings up the basic cancer mechanism, in such a simple to understand pictorial form, right up front.

    “The great advantage of knowing the prime cause of a disease is that it can then be attacked logically and over a broad front. This is particularly important in the case of cancer, with its numerous secondary and remote causes, and because it is often stated that in man alone there are over one hundred well-known and quite different kinds of cancer, usually with the implication that therefore we will have to find one or several hundred bases for prevention and treatment, and usually without any realization that this need not necessarily be the case now that we know that all cancers studied have a characteristic metabolism in common, a prime cause.” Doctor Otto Warburg , Note what Doctor Warburg says applies to ALL DISEASE!

    What the brilliant Doctor Warburg gave us is the cause of MOST if not ALL cancer.

    “Just by decreasing a cell’s oxygen content by about one-third, cancer is automatically induced. Nothing more is required for cancer to develop.” Doctor Otto Warburg 1924

    These few earth shaking words are the KEY to MOST cancer. Note that it is the lack of oxygen that is the basic problem; cancer does not REQUIRE the encapsulation by a tumor to begin. There are MANY “foods” that promote this lack of oxygen delivery to the cell, with processed vegetable oils and “fast foods” being only the two most egregious of dozens slightly less carcinogenic. Another brilliant doctor, doctor Andrew Moulden has shown us another powerful method to keep oxygen from reaching our cells.

    “ALL vaccines are and have been causing ischemic (impaired blood flow) damages – to all – creating a plethora of chronic illnesses, disease, and in some instances…death. The injury from vaccination is additive, each vaccination further injures.” Doctor Andrew Moulden MD, PhD

    With Doctor Wargburg’s brilliant discovery that the lack of OXYGEN is the BASE cause of most cancer; cancer SHOULD have been solved MANY decades ago.

    I can tell you WHY cancer has not been solved but no one will publish it so lets go from here.

    DCA OBVIOUSLY would be declared as a PRIME anti-cancer drug candidate by Doctor Warburg. DCA addresses and appears to thwart, at several points and by several methods, the basic cancer process..

    DCA MAY have some toxicity but after over a decade in the field I can tell you for sure it has far LESS toxicity than most chemo drugs. DCA appears to be at least an order of magnitude more efficacious than most cancer treatments. Incidentally IV Vitamin C in doses up to 300 grams is PROVING to be an Ideal chemo.

    So lets see, here we have DCA a brilliant candidate drug tor cancer treatment but the Cancer Industry is not interested. Should we be surprised?

    When I was a kid we called a certain disease SUGAR Diabetes, now it is called Type II Diabetes. Why? Do you think just correctly naming a disease could help VASTLY in it’s prevention? Might people just stop eating sugar if they were afraid of SUGAR Diabetes?

    DCA is not that hard to understand. You need to learn the correct dosage and administration protocol. DCA has proven not that toxic in over a decade of FDA approved clinical use. DCA appears to thwart the cancer process by several methods of action. If I or a loved one gets cancer you can bet DCA will be a prime candidate as a treatment. There are MANY salubrious cancer treatments.

    Meanwhile 99+% of us can sleep well knowing we have little risk of getting ANY cancer if we assure that each of our 10 trillion cells receives adequate oxygen; we are aware of the MANY anti-cancer methods our body’s possess; we are aware of the hundreds of foods, herbs and supplements proven to be anti-cancer.

    http://healthyprotocols.com/2_cancer.htm


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